Over the past three to four years, Health-USA has been trying to expand its operations with a new set of services and solutions for patient-centric care delivery, care coordination, and clinical decision support. Recently, the company decided to implement Internet of Things (IoT) devices and sensors as part of its strategic IT plan. In this Advisor, I present a case study of Health-USA’s experience leveraging the combination of enterprise architecture (EA) and IoT in its digital transformation effort and share a set of effective practices gleaned from that effort.